Oh Jeez--I feel for all you knee people on here. I am a 65 year old retired oncology nurse. I had a TKR in 2010 and a MUA about 3 weeks after that. In the past 17 years, not the greatest ROM but I learned to live with it. I found if I rode my bike religiously--and I wired my left foot onto the pedal--since it wanted to slip off due to stiffness--if I rode my bike daily, I could keep my ROM. But I found it utterly AMAZING that if I didn't ride my bike every day, that by the next day of riding, my knee was very stiff again. Wow--that is some kind of tissue/adhesion growth rate!! So basically, I rode my bike 10-15 miles a day out of utter fear. In 2017, I got an ugly debilitating infection in the TKR and ended up going to the hospital via 911 and having it immediately debrided. I was on antibiotics for 7 months and was told by my infectious disease doc that ultimately, I would need to have it re-done since the infection would always be in there--silently smoldering. I have taken a chance by stopping the antibiotics and not having the surgery. So far so good. But I am kinda waiting for the other shoe to drop. In the meantime--THE DEBRIDEMENT HAS INCREASED MY ROM HUGELY!!! While my knee is ugly and swollen and criss-crossed with suture lines, I feel unbelievably lucky to have been able to have the emergency debridement and the subsequent increase in ROM. I have been to 3 different ortho people and they all say--"Don't mess with it. Leave it alone." The 4th one said "You will really regret not having this new TKR done now--when you are still 65 and fairly mobile. It's gonna be a lot tougher on you with each year that passes--when the infection flares up and you get back in serious trouble." Well, that may be the case--but in the meantime, I am enjoying my mobility and will cross the bridge when I come to it. I have a question about the stem cell ads I see in the newspaper. Can someone kindly tell me about it, if it could work for me, and what its goals are? Thank you. Love, Mary Ann