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mike0157 avatar

Anyone following a wait and see with a Gleason 3+3

Prostate Cancer | Last Active: Aug 27, 2025 | Replies (20)

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Profile picture for floridanad @floridanad

My recommendation is always get a 2nd, 3rd, or even 4th opinion, and go to a cancer research center like Mayo or Moffitt for ongoing treatment. They are THE experts on prostate cancer and are on the cutting edge. This is what they do, everyday, 7 days a week, 365 days a year.

I was recently diagnosed with Gleason (3+3) 6, PSA 5.5, biopsy (one cell positive out of 12). Decipher score LOW. I also have hypogonadism (body does not produce testosterone) and have been taking testosterone injections for a decade before my diagnosis and was stopped. Specialist at Moffitt Cancer Center put me on active surveillance and allowed me to continue taking testosterone injections - which all other urologists refused. But the specialist at Moffitt has other patients in his practice in my situation that are receiving testosterone and on active surveillance.

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Replies to "My recommendation is always get a 2nd, 3rd, or even 4th opinion, and go to a..."

Has your PSA continue to rise while you were getting those testosterone injections, Or has it stayed pretty much about the same or risen very slowly.

After having your Testosterone injections. How high does your testosterone actually get?

I guess they figure, people on active surveillance have full testosterone, so why not give it to you too. It definitely doesn’t seem to be as problematic to do, as it would be with people who have active prostate cancer.