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Anyone following a wait and see with a Gleason 3+3

Prostate Cancer | Last Active: Aug 27, 2025 | Replies (20)

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Thanks. would you mind sharing what Gleason and PSA you started with and what after 9 years changed that caused the treatment decision.

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Replies to "Thanks. would you mind sharing what Gleason and PSA you started with and what after 9..."

For the previous 12 years that I had been tracking my PSA, it rose from 1.3 to 4.0. At that point I had a biopsy that showed a Gleason 6(3+3). I chose active surveillance.

Over 9 years, I had 3 more biopsies, the first 2 were 3+3, the last one was 3+4. Over that same time I had PSA tests every 4-6 months; my PSA increased from 4,0 to 8.0.

Also, a Prolaris biomarker test indicated that I had “exceeded the threshold for active surveillance.”

It was then that I decided on active treatment (proton radiation).