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mike0157 avatar

Anyone following a wait and see with a Gleason 3+3

Prostate Cancer | Last Active: Aug 27 3:11pm | Replies (20)

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I was one that decided to over treat. gleason 3+3, 1 out of 12 samples with cancer, PSA 1.1. Age 68. I convinced my Dr. into NSRALP. Father with an awful death from prostate cancer, grandfather, a brother. I decided i just wanted it out. Medicare paid for it. Post op 2 small lesions contained in the prostate , clean margins, 3+3, no lymph involvement. I am both incontinent and have ED issues. Its been 6 years clean PET scan, < .01 PSA. No other health issues. Did I roll the dice and win or did I roll the dice and lose. ? good question. Most times I wonder if waiting was the best answer.

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Replies to "I was one that decided to over treat. gleason 3+3, 1 out of 12 samples with..."

I wouldn't second-guess your decision. Someone has to take *all* the risk factors into account, not just the Gleason score. Do they have germline mutations like BRCA1/2, that can make cancer more aggressive? Had their PSA risen rapidly between annual screenings (if they were getting them)? Do they have a strong family history of advanced prostate cancer?

In your case, the answer to that last question was "yes", so I think you were justified in seeking more aggressive treatment, for whatever my opinion is worth. But for someone who answered 'no' to all of those questions, active surveillance for 3+3=6 would likely make the most sense.