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← Return to How long were you on Orgovyx, Xtandi, Talzenna? Fatigue unbearable
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How long were you on Orgovyx, Xtandi, Talzenna? Fatigue unbearable
Prostate Cancer | Last Active: Aug 6 7:49pm | Replies (65)Comment receiving replies
I started on Xtandi feb 24.
My PSA was 0 (zero) as of August 2024 and my xtandi was reduced to 40mg a day.
Still fatigued, brain fog and issues with short term memory . But small potatoes considering the alternative...
Aug 1, 2025 I'm replacing Xtandi with something called NUBEQA which is supposed to act like Xtandi but cut the immense fatigue in half.
My issue with Xtandi really has been an inability to focus but I'm learning to expect less of myself. Somethings that used to take an hour now seems to take 6 hours.... and that is my new norm.
I'm stage 4 Gleason score 9
Replies to "I started on Xtandi feb 24. My PSA was 0 (zero) as of August 2024 and..."
Is it possible for my nubeqa to be reduced if my next psa level is good? Of course I'm on injection ls every 3 months and have metastatic cancer so probably not
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Nubeqa does not pass the blood brain barrier so it doesn’t cause the brain fog like Xtandi.
I would imagine you are on an ADT drug. A common problem with ADT drugs, over time, is they cause brain fog. Are you on Lupron, Eligard or Orgovyx or something like that?