In response to jay0013:
I was a Pluvicto clinical trial patient 2021-22 and responded remarkably well. It was a full 22 months after the final treatment before my PSA began to rise again and tumor growth was detected. The only side effects (other than being radioactive) were a day or two of feeling a little funky from the Lu-177 and some, but minor fatigue toward the end of the 6th treatment.
I am now repeating the 6 treatments (completed #4 of 6) via a special arrangement with Novartis Pharmaceutical and Medicare. Fortunately, it is working incredibly well once again. It has saved my life, twice and I'm leading a virtually normal, active life. Yes, it will return at some point, but considering I'm in my 10th year of metastatic castration-resistant stage 4 prostate cancer, it's wonderful to keep kicking the can down the road a couple of years with each round of treatments.
Stay informed, do your homework and don't give up.