I was diagnosed at 62, After surgery, it was a 4+3. I had surgery 15 years ago and 3 1/2 Years later, it came back so I had salvage radiation. 2 1/2 years later came back. I started Lupron and 2 1/2 years later, I failed Lupron, which is called castrate resistant. Started on Zytiga, Which kept my PSA low for 2 1/2 years and then I switched to Nubeqa and I’ve have been undetectable for 20 months
Found out Four years ago that I have BRCA2. That’s why I got it at 62 but my brother got it at 75. We both had the same father that died from it, but he didn’t have BRCA2 Which causes it to occur younger.
I bring this up because I’m wondering if you’ve had hereditary genetic testing yet. Have people in your family had cancer or prostate cancer? Has it been offered to you by a doctor? You can get it done free with the below link, if you live in the United States. Do not check the box that you want your doctor involved or they won’t send you the kit until they get in contact with your doctor. It takes about three weeks to get the results and then a genetic counselor will call you.
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Prostatecancerpromise.org
Surgery and radiation have about the same result but surgery can cause serious ED. If they can save the nerves that can help a lot. There are a lot of solutions to ED. Some people get implants some people really like the injections. If you have radiation, there’s also a risk of having ED two or three years after treatment.
Most people do not become incontinent, Though it may be difficult for the first few months. I started having some incontinence problems six years after radiation. It’s not too bad if I take a pill, which makes it a lot better.
Definitely consider proton radiation. It is used with children who have cancer that has to be treated with radiation because it has a very low chance of causing cancers of other organs. You might live 30 more years and if you have radiation in 10 or 15 it might be an issue.
For a Gleason 4+3 ADT is recommended for six months. That’s pretty easy to live with, I’ve been on at eight years, Not as easy. If you get Orgovyx for ADT Testosterone usually comes back quicker than with other ADT drugs. You should realize that ADT does not kill the cancer. It just stops it from growing.
I live what most people would consider a normal life. You would have a hard time figuring out I have cancer. To offset the side effects of the drugs, I walk on a track twice a day, 1 mile every day. I also get to the gym usually three days a week. You’ve got to use weights and exercise exercises in order to keep your bones strong.
You should consider getting a second opinion from a center of excellence. You could also find a Genito Urinary Oncologist, They are the ones that specialize in prostate cancer and can guide your treatment with other doctors.
Honestly one of my major concerns is doing the Robotic Assisted RP and either immediately or later on having to do salvage radiation + hormonal therapy. My pathology report did mention that the Cribriform pattern was present which from everything I can find is NOT a good thing. This makes me think that recurrence is probably likely. The Radiation Oncologist didn't seem particularly concerned with the Cribriform pattern being present.
My father had prostate cancer in the 1980-1981 time frame unfortunately I don't know any specifics concerning type or treatment other than he had surgery. He never had any further incidence involving prostate cancer for the remainder of his life (he was ~60 at the time of surgery). The Radiation Oncologist does want to do genetic testing my Surgeon/Urologist didn't mention any plans for the additional testing.
Thanks so much for the good news concerning Orgovyx/relugolix as this is what my Urologist plans for the ADT Treatment, that certainly helps to minimize my strong concerns regarding that leg of the treatment. My Radiation Oncologist told me that IMRT is essentially on-par with Proton treatment; however, it's difficult to evaluate this statement since the available data for Proton treatment is small as compared to RT. I travel to Emory in Atlanta next week to get an additional opinion. I'm truly 50/50 on this but the worst case in my mind would be to have to go through RP, Radiation and ADT all.