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Hyperparathyroidism caused osteoporosis--now what treatment?
Osteoporosis & Bone Health | Last Active: Jul 30 8:15am | Replies (55)Comment receiving replies
I Didn’t know which thread to put this on so sorry if I’m incorrect.
Here’s what I sent to my Endocrinologist and her reply.
I don’t understand it.
“Hello Meridith,
We have checked one of the bone turnover marker COLLAGEN XLINK N TELOPEPTIDE,UR,RANDOM.
Component
Ref Range & Units (hover)
2/9/24 1439
N-Telopeptide
39
Comment: Note
Adult Female Reference Range for Collagen Cross-
Linked N-Telopeptide (NTx), Random Urine
Premenopausal: 4-64 nM BCE/mM creat
Component
Ref Range & Units (hover)
7/2/25 0907
N-Telopeptide
60
Comment: Note
Adult Female Reference Range for Collagen Cross-
Linked N-Telopeptide (NTx), Random Urine
Premenopausal: 4-64 nM BCE/mM creat
Again those bone marker are not for making decision on treatment options. Those are somewhat useful to monitor once you have started on osteoporosis medications.
Best regards, “
Replies to "I Didn’t know which thread to put this on so sorry if I’m incorrect. Here’s what..."
Hi @meri8181, your uNTX, which is a bone resorption marker, seemed to trend upward from 2/2024 to 7/2025. I noticed numbers like 1439 and 0907 next to the dates - maybe those are time stamps? Like CTX, uNTX levels can vary depending on the time of day - they tend to be higher in the early morning and lower later in the day. If the urine collection times were different, that might explain the change and there may not be a big shift after all.
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Meri8181,
random means the specimen can be taken any time of day. The test ordered is NTX urine measuring product left in the urine by bone breakdown. The comparable serum level is called CTX.
She would be ordering this to establish a baseline And will measure it again after two to three months of antiresorptive treatment to ascertain that the medication is slowing the breakdown in nanomoles of bone collagen equivalents (BCE)/mM creatine
The normal range for this test is 4-64. You are at 60
The doctor includes a disclaimer, saying that the numbers are not used for making decisions about treatment. Which I assume means that she hasn't ordered with the code for medical necessity and may make it difficult to receive insurance coverage for the test.
Meri, which medication have you decided to take.