thanks for the update. The cream comes in different strengths. My doctor recommended the 4%, but online I see that there is a .5% that is milder but a lot more expensive. I am nervous about using the cream on my face - a larger area than you describe - so I am considering getting the .5%. There is very little that I can find about it. One thing is that it seems to less systemic than the 5% solution - which is known to cause side effects like stomach issues. I am trying to find out if the .5% percent is truly less of an irritation both to the skin and to the body in general. I have also read about daylight PDT which is available in Canada and also in many parts of Europe - but I cannot find it in the US - so trying to follow up on that as well. Curious - if it is just one spot - did they zap it with the freeze thing? I thought the cream was for stuff that had not yet surfaced.