It was Abbie. A known problem with the drug is its effect on the heart. It also caused me to have 4 afib events. Three of them they just shocked me back into normal rhythm. I was on ADT for 2 1/2 years before getting on Zytiga And I had no cardiac issues at all.

One afib event put me in the hospital for four days because I had taken an antibiotic that affects the electrical system. I went into a fib and they couldn’t shock me out of it until that anabiotic had become ineffective and that was going to take four days (long half life). My pulse was 175 standing and 125 laying down for 3 1/2 days, Then on the third day they gave me metoprolol And within one hour, my pulse went back to normal.

I have done the exact same thing that caused afib, over and over, since I have stopped taking Zytiga, without any problems.

My oncologist insisted I stop Zytiga and At first, she wanted me to switch to a PARP Inhibitor, But after a few days, I realize that I would be much better off going to Darolutamide, So I talked to her and switched drugs and was now able to reduce the amount of cardiac medicine I’m taking.

A couple of things have changed as a result, however. My cardiologist had me on carvedilol As a beta blocker. Another cardiologist, I know said that he took metoprolol Whenever he felt like he might have his pulse rising, leading to AFib. I was already having problems with the beta blocker. I was on, My pulse would rise suddenly walking 10 feet.

I told my cardiologist I want to switch from carvedilol to metoprolol, and it’s made a major difference. Even if I exercise hard and feel like my heartbeat should be excessive. It’s never over 120. The beta blocker prevents it from going any higher..

Just putting in some things, I’ve learned due to these high blood pressure problems.