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DiscussionHow long were you on Orgovyx, Xtandi, Talzenna? Fatigue unbearable
Prostate Cancer | Last Active: Aug 6 7:49pm | Replies (65)Comment receiving replies
Replies to "I just realized that you were on a PARP Inhibitor (Talzenna). They are only usable for..."
There have been clinical trials investigating using PARP inhibitors in combination with ADT+ARSIto treat mCRPC, regardless of germline mutations, but I don't think any has made it into mainstream care yet.
Example:
https://evidence.nejm.org/doi/full/10.1056/EVIDoa2200043