Thanks for your reply. The doctor I had during the trial is a world leading specialist in NTM/MAC. The consultant overseeing my care after admission last week told me I HAVE to have ethambutol and Rifampicin alongside amikaycin (IV initially) and ethambutol on the regimen as only having a 2-drug regime has very high risk of making the mycobacteria avium anti biotic resistant. I have done extensive research over many months (not quackery but bonafide clinical data) that correlates with the opinion that rifampicin may have little of no benefit in treating MAC successfully. I’m currently awaiting results on my latest sputum sample to determine whether, now, I am already anti biotic resistant.