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Yes, but how do you know aggressiveness of your cancer without biopsy and decipher ? According to my husband's PSA and MRI nobody would guess that he actually has very aggressive cells in his prostate - cribriform and probable IDC.
Also - a comment about melanoma is bogus ! One has to have a skin biopsy to make diagnosis and what is a biopsy but cutting into that particular mole or spot and looking it under the microscope. According to him that would spread melanoma and be malpractice !!! Just insane statement and he lost any credibility for me after that sentence - period.
The only sentence that he uttered that was of importance was that this video is more so about his philosophy about living - well, I prefer to rely more on studies and results than on his philosophy , but that is just me.
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Great question…apparently biopsy/Decipher score is currently the best way to determine aggressiveness; but even Gleason scoring is inaccurate in 20–30% or more cases, even at Centers of Excellence, according to Dr. Matt Cooperberg.
However, once diagnosed with low risk PCa, I believe we are very close to having noninvasive tests (such as MyProstateScore 2.0 - MPS2) which will eliminate the need for follow-up biopsies for those on Active Surveillance….possibly by the end of 2025.
Regarding your other comment:
Cutting around the margins (excisional biopsy) is the gold standard for a suspected melanoma, for a variety of reasons, including “seeding”, although spreading cancer through cutting into tumors is apparently rare.
Although metastasis, due to biopsy is apparently rare, it does happen.
Hopefully, biopsy methods are ever improving; but it’s a demonstrably fact that CTC’s are elevated after prostate biopsy.
A 2014 study showed 84% of men had elevated CTC’s 30 minutes after their biopsy.
The entire point of this thread is that prostate complications (other than the well known infection complication) can happen…I’m living proof.
I don’t fault the medical establishment for my “rare” negative biopsy side effect.
Even my urologist admitted it does happen, one in half years after I asked him about my experience.
Unfortunately, “rare” side effects are not mentioned in the prebiopsy “fine print”, as the thinking goes that it will only scare and discourage men from doing the only thing the industry knows to do.
Fair enough, but I for one decided not to remain silent, regarding my biopsy experience, just because it may ruffle a few feathers and it is considered “rare”.
Information is sometimes inconvenient and there are no guarantees even for the seemingly mundane…