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canderson5 avatar

Kisqali and Letrozole have heart issues?

Breast Cancer | Last Active: Jul 26 5:33pm | Replies (25)

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Good to hear you’re doing okay. Thanks for the info regarding the 200 mg dose. I started on 600 but that gave me dangerous QT prolongation. I have been on 400 for 4.5 years and dealing with paroxysmal AFib ever since that started on day 5 of Kisqali but 8 days before I started Letrozole. I purposely started Letrozole two weeks later hoping I would know which med caused which side effects. My oncologist tells me the AFib is unrelated. Right. Heart rhythm issues are even in Kisqali’s own literature. I will be asking the EP his thoughts on Kisqali and AFib. Thanks again for the reply. Best to you going forward.

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Replies to "Good to hear you’re doing okay. Thanks for the info regarding the 200 mg dose. I..."

My cardiology told me that Kisqali may cause QT prolongation issue and letrozole may cause AFib. The QT prolongation issue is stated as a side effect on Kisqali manual, though the AFib is NOT listed as a side effect on Letrozole manual. But you said you have AFib before taking Letrozole. It seems that the Kisqali shall be the reason.