← Return to Cribriform cells: Does their presence change treatment approach?

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Thank you for replying in detail! My husband 68 years old, non diabetic and non hyper tensive, non smoker, has acinar adenocarcinoma stage II. On both sides of prostate but within the prostate. 3 out of 15 cores positive. first core 10% 3, second 15% 3 and the third one 25% consisting of 19% 3 and 6% 4. No cribiform. PSMA pet can and MRI clear except for the prostate. I think there were 3 areas on the prostate, 2 of them less than 5mm and 1 was 10 mm. biopsy done 30th april. surgery may be in Oct. Just wondering if the wait is too long. Surgeon is very experienced wth good ratings. refuses to precribe ADT while waiting 6 months. Can you tell me how long you waited from date of bipsy for surgery and if you were prescribed any medication during the wait? Thank you.

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Replies to "Thank you for replying in detail! My husband 68 years old, non diabetic and non hyper..."

You need to find a more supportive doctor. Your doctor does not appear to be aware of how six months could be a major factor in someone’s cancer growth if they are not on ADT. Yes, it grows slowly, but not even considering putting him on ADT is a problem.

Did you ever speak to A radiation oncologist, about radiation instead of surgery or even one of the other treatments that work quite well with somebody that has cancer a your husband‘s level. Here are Non radiation treatments your husband could consider HIFU , Cryoabalation , NanoKnife , TULSA PRO, HoLEP.

It sounds like you found a urologist who really isn’t experienced enough for modern treatments. You would be much better off, going to the Mayo Clinic or finding a Genito urinary oncologist, They are the ones that specialize in prostate cancer.

There is no reason your husband should wait six months for treatment.

I really believe that your surgeon is giving you good advice. My surgery was originally scheduled to be six months from my biopsy, like your husband's. I consulted widely before my surgery. I spoke to two Urologists here in Alberta, and I travelled to the Mayo Clinic in Florida to have private consults with another Urologist and a Radiation Oncologist. All agreed that surgery was the best option for me and that waiting six months should not be a concern. And remember, my cancer was significantly more aggressive than your husband's. My cancer had extended outside of the capsule of my prostate, it had Cribriform and was Gleason 4+3.

I remember, when I asked the Radiation Oncologist what he would do in my circumstance, he said that he would opt of surgery over radiation because of the adverse side effects of ADT that would be part of the radiation therapy.

I also asked him if he would opt to pay for surgery out of pocket to get it early and he had a humorous response, but he meant it. He said: No, I would use the money to go on a long cruise and would wait for surgery in six months without worrying about it.

In summary, from the information you provided your husbands cancer does not have aggressive characteristics and from my research and consults, I do not think waiting six months for surgery is too long. In your husbands circumstance, I would not consider taking ADT before surgery. The side effects of ADT are supposed to be very unpleasant.

Finally, make sure your husband is getting the Robot Assisted Radical Prostatectomy or RARP surgery.