I've had four breast biopsies over the last couple of months; the first two were pretty fine though I was quite nervous, and I was specifically instructed to say if anything started hurting at all during the process and they'd stop and give me more lidocaine, which I did indicate a few times. It was more of a momentary sharp/pokey feeling a few times, and then the extra lidocaine made that go away.

The last two were an MRI-guided biopsy and another sterostactic one. The MRI-guided one hurt my body a lot but not my breast, only because I had to be in such an incredibly awkward position for over an hour and not move - my back and shoulders were seriously hurting by the end, which I don't normally experience.

My very last biopsy was the only actual biopsy that really hurt - I was almost screaming at times. Also there was a lot of blood, I noticed afterwards. They were apologetic and said it was hurting so much because the biopsied spot was so close to the nipple, where many nerve endings are. They tried to give me more lidocaine a few times but it barely did anything, in contrast with my other experiences. That spot also ended up being the one with invasive cancer, which makes me wonder if doing a biopsy within a lump hurts more? I think it was likely just the proximity to the nipple.