Thanks, Linda. I'm on the big 3 now, in the middle of my 6th week. The worst adverse effect is GI trouble: intense, sometimes prolonged (hours and hours) intestinal cramping after the first two weeks, often without much or any diarrhea. At one point, my doc suggested NJH, which prompted my question. I've changed the timing and order of taking each of the 3 and so far (fingers crossed!) that's helped. I live in Colorado, not that far from Denver, but just can't see spending a week in the hospital. So, I was hoping someone has been able to get a consult about new meds without all the re-testing and extreme inconvenience.