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← Return to Post Evenity DEXA numbers
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I did all possible adjustments including GE and Hologic conversion from g/cm2 to mg/cm2 based on the online conversion “app”. Femur ranged from 6.5% - 19.3%, Spine from 10.9% - 35.8%; down from my original comparison using T-Score. I’m thrilled! All the hard work seems to have paid off in some respects.
I met my new endocrinologist today and she recommended Prolia for 3-4 doses and switch back to Evenity to build more bones. Evenity needs at least 1 year sabbatical (😜) before going back to. She said Prolia is a stronger medicine than Reclast; as long as there is follow-up switch to a different med, the rebound fracture issue should not be too serious. I was originally inclined to do Reclast but now am thinking of Prolia as a transitional med before Evenity again.
What’s your thought on this? Thanks!
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These are very impressive gains— congratulations!
I've read that a few members on this forum followed a similar path: they used Evenity first, then transitioned to Prolia for 2-3 injections in hopes of achieving further BMD gains. Based on their posts, they're planning to switch to Reclast after completing the Prolia doses.
Your endocrinologist makes a valid point about taking a one-year "sabbatical" from Evenity. I believe it was during last year's Santa Fe Bone Symposium that several specialists mentioned the idea that "bone doesn't want to keep building" indefinitely.
There is a clinical study (small) that looked at a sequence of Evenity → 2 Prolia injections (1 year) → Evenity. BMD outcome is shown in the graph below. The full publication link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6877701/
Keep in mind, though, that this study used a shorter duration of Prolia than what your endocrinologist is proposing. As many of us now know, the risk of rebound bone loss increases with more doses of Prolia. If you end up having four injections, will Evenity's antiresorptive effect be strong enough to counteract a potential rebound? That's definitely something worth discussing with your endocrinologist.
Are you able to take a bisphosphonate orally?