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Just Finished 18 mos on Tymlos and....

Osteoporosis & Bone Health | Last Active: Jul 25 2:26pm | Replies (38)

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Profile picture for gowalking @gowalking

I have heard of the "holiday" but am leary of it.
My bone doctor said my sudden drop in density was caused by stopping prolia in preperation for a dental implant.

I was being treated by my GYN and was told by her PA to go off the Prolia before the dental work, then get my next shot immediately after. I was due for my six month dose, a few weeks after the dental work. In that short time my bones
weakened dramatically. A trip to the ER showed a fracture, I had surgery on that one. Then four more fractures immediately after.

For that reason, I'm petrified of a "holiday". But I cannot stay on the Tymlos longer than two years.
I now see a bone specialist and am anxious to know what treatment she advises post Tymlos. I've heard reclast can be a once a year drip or twice a year injection. I'd love once a year. Is that for the rest of your life or is there a maximum time for Reclast also?

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Replies to "I have heard of the "holiday" but am leary of it. My bone doctor said my..."

There's no Prolia holiday. The way it works, if you stop, the rebound effect will cause rapid bone loss. You cannot stop Prolia and not take any more drugs.

Drugs like Fosamax and Reclast are different. You can have holidays with those, during which you'd be monitored.

I had a horrible rebound effect from stopping Prolia, too, and not being put on something stronger than oral bisphosphenates to counteract it. That’s one you can’t take a “holiday” from without a plan for another medication. I’m not sure about the maximum Reclast dosage or whether it’s available as an injection, I was under the impression it was only as an infusion. I’m glad I know my doctor now will order labs to keep a check on my BTMs, no matter what I am on or not on. Best of luck and health to you!