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DUPIXENT (dupilumab)

MAC & Bronchiectasis | Last Active: Jul 28, 2025 | Replies (18)

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@blm1007blm1007 I have been taking Dupixent for 7 months for asthma, BE, eczema, etc. (Also have Lupus and deep chronic lung infection).
Dupixent has helped, no side effects. The company calls to check on side effects often in the first few months.
I had chronic cough and out of control asthma for 8 months prior, with steroids and benzonatate as treatment until bronchoscopy showed infection. Antibiotics, anti inflammatory diet, and benzonatate are tamping down the infection and cough. Both lower lungs are affected, but I am doing well. If your doctor suggests it, I recommend following through with it.

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Replies to "@blm1007blm1007 I have been taking Dupixent for 7 months for asthma, BE, eczema, etc. (Also have..."

I'm curious if you have a high eosinophil counts and which of your conditions was the indication for it. I just got a sample dose for urticaria.

I was just doing a quick review to respond to Barb and it seems high eosinophil counts are part of indication for its use. About 20% of bronchiectasis patients have high eosinophils-mine haven't been elevated.

@ pacathy
Thank you both for reading and responding.
I understand from a neighbor who has had Eczema since childhood that the Dupixent has done wonders for her.
Regarding the benzonatate I researched it and this is one thing it said regarding it. Were you told of this?
"It should not be used for chronic coughs associated with smoking, asthma, or emphysema, especially when there's excessive mucus production?" True it doesn't specifically say BE.
Did you have excessive mucus production before taking it.? Do you have excessive mucus production with taking it? I do have excessive mucus all day long. I also read somewhere on a BE Mayo thread.......don't know if it was you.....that the BE patient takes the benzonatate, mostly, if I understood correctly, a bit before going out when she is being social, restaurant outings etc.
It is interesting that no doctor has suggested to me to do the anti inflammatory diet, however, I have been doing my best to follow it. I also watch what I eat as a precautionary measure due to NJH belief that acid reflux plays a role with BE. So I also follow as best I can the acid reflux diet.
Regarding @pacathy mentioning eosinophils, mine are not elevated. However, my Neutrophils (showing infections and inflammation) are right on the border line of normal/high...about to go over to the high side.
Barbara