Being treated for Gleason 9

Based on a study of 10,415 prostate cancer patients (intermediate to high-risk) I'm guessing your chances of surviving your PCa for at least 10 years are very-good-to-excellent!

Of course, a lot depends on how YOU respond to treatment.

For starters, hopefully at some point your PSA will drop to virtually undetectable (below 0.01 ng/ml) while taking Orgovyx.

And 6 months AFTER completing treatment...

"The 10-year prostate cancer-specific mortality rates for patients with a PSA nadir of 0.1 ng/mL or higher were 14%, 15%, and 14% for the patients who received RT alone, RT plus short-term ADT, and RT plus long-term ADT, respectively. The rates for patients with a PSA nadir less than 0.1 ng/mL were 8%, 7%, and 7%, respectively."
https://www.renalandurologynews.com/news/psa-nadir-after-rtadt-for-prostate-cancer-predicts-outcomes/
https://meetings.asco.org/abstracts-presentations/218387

Thanks for this. Now I know what I'm looking for.👍

Which of those trials are with radiation?

I'm also Gleason 9, age 67, had surgery in November. I had several indications that recurrence is in my future. Present in cribriform glands, bladder neck, Lymphatic or Vascular Invasion, perineural, multifocal and presence at the margins. My 8-month PSA was 0.02. So far my urologist is taking a wait and watch approach. Next scheduled appointment is my next PSA is Oct. 1. It's difficult to be patient because everything I see online says all of those conditions are bad. I'm probably going to have a consultation with someone else just to make sure my course of treatment makes sense.

I know that my doctor would have me getting three months PSA tests at least for a couple of years.

I Have been getting monthly tests for eight years. I’ve been undetectable for 20 months, but it could come back any day now so I get monthly tests.

The STAMPEDE trial did: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32486-3/fulltext

You’ll have to research each one (and more recent ones).

There are many studies (even beyond those in that table). In fact there are randomized phase 3 studies (PEACE-1 and ARASENS) demonstrating the superiority of triplet regimen over doublet treatment.

You may have to do some research.

In 2015 I had a biopsy done 'cause my PSA was 13 retested It was 14. Had a biopsy and I was told 75% of 12 snips were cancerous. Of course I had options. I elected to have it removed. I'm 67 now. I was told that I would live a normal life should everything be successful. Unfortunately that was far from the truth. Although I have detested undetectable coming up on 10 years in August I am grateful. Beyond what I imagined could happen. But they never discussed anything to do with Gleason numbers so I don't even know what that means or what mine was. I do remember my urologist who did the surgery and I had The non invasive Robotic prostatectomy. And I was told that if everything goes well I should live 20 more years. I guess I have 10 left. I thought that was an odd thing to say. Either way maybe I can get some input on the Gleason numbers And should I even go back at this point and talk to them about it.
thanks for anyone's input.
Paul

Definitely go back and ask for a copy of your original biopsy. It will have your Gleason score and more.

Hello Donald, I had my prostate removed in April 2019, gleason 4+5. Decipher was .96. One lymph node positive. All scans showed no cells anywhere else. PSA undetectable 6 months post op; still undetectable 6 years later. I had 39 radiation sessions, in 2019, and 2 years of Xytiga with prednisone. I am now 79 years old. I consider myself very lucky, at least so far. I hope you have a cancer free future.