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Profile picture for projfan @projfan

I'm sorry you turned out to be a non-responder to semaglutide -- some people just are, unfortunately. Zepbound is a combination of another GLP-1 RA and a GIP, and some people do respond better to one drug than the other. The nausea and vomiting are common side effects, and I can definitely see them as more likely for someone who goes up sharply in dosage rather than gradually.

If you are still interested in serious weight loss, you might want to consider bariatric surgery. Nothing is the perfect answer for everyone, so this might be a better option for you than the drugs. It also has the advantage of being one-and-done.

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Replies to "I'm sorry you turned out to be a non-responder to semaglutide -- some people just are,..."

@projfan
For me it is the snacks. I am an emotional snacker and when upset, stressed, or worried I tend to snack as a treat to feel better. Problem is one of my most liked snacks are mixed nuts. Now they are suppose to be good for you but are high calorie. 1/4 of a cub is 180 caloried. A 1/4 cup of nuts does not even fill up your hand.

My meals are pretty much normal size, and I am not a big sugar person. I also exercise about 12 hours a week. So not a lazy person or couch potato (I almost put the "E" on end like Quale).

Over the last 5 years I have become a care giver for my wife. She developed type one diabetes about 5 years ago caused by damage to her vagus nerve during stomach surgery (3 of them). Then she had back fusion surgery, sinus surgery. So was really getting depressed and of course snacking.

Then just as things were getting better in 2023 diangosed with prostate cancer. Got that successfully treated and then in 2024 got COVID for first time that went into severe sinus infection, then bronchial infection. Kept me down for 3 months.

Then just as feeling better my wife's diabetes caused damage to a nerve in her left eye and she developed double vision. Has to have surgery but we can't get her A1C under control to have it. We got prescription for prism glasses (supposed to correct double vision) but did not work. So she has been wearing a patch over one eye now for about 6 months.

So even if I wanted to have surgery (and I don't) just would be impossible to fit in being a care giver. Sorry for the long post sometimes feels good to speak out.

I don't want anyone reading my post to hesitate to do what is best for you because I had a severe reaction to the 2.4 level dose of WEGOVY. I know a lot of people that did have same reaction and went back to the 1.75 dose level and they are doing fine losing lots of weight.

Great medication for those wanting to lose weight. I think the new pill form will even be better.