@kb2014 Could you help me to better understand your diagnosis? From what you’ve written I deduced that you have significant gastrointestinal problems due to both the removal of your gall bladder and your prescription for an anti-epilepsy (sometimes referred to as anti-seizure) medication. Are you prescribed the anti-seizure medication for anxiety or depression? Or have you been diagnosed with epilepsy? Since you’ve been seeing a neurologist I am thinking the medication is for epilepsy. Is that correct? I ask this because anti-seizure medication is often prescribed for mood stabilization.

I have posted information from Mayo Clinic on how anti-seizure medication is used for mood stabilization. I’m not suggesting that you have Bipolar Disorders - I’m only posting this as an example of how anti-seizure medication can be helpful disorders other than epilepsy.

Mayo Clinic Bipolar Disorder: Diagnosis and Treatment (be sure to read to the bottom of this page as there is information on how anti-seizure medication is used for mood disorders).

— https://www.mayoclinic.org/diseases-conditions/bipolar-disorder/diagnosis-treatment/drc-20355961

There are many medications that produce gastrointestinal side effects such as Zoloft as @wishingonastar describes in the original post.

The brain-gut interaction theory has been the subject of research for a number of disorders including mood disorders.

Mayo Clinic: Heal your Gut, Save your Brain:

- https://mcpress.mayoclinic.org/nutrition-fitness/heal-your-gut-save-your-brain/

@kb2014 Have you been diagnosed with anxiety or depression?