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How long does your oncologist have you on ADT?
I had surgery in March 2020. I was undetectable for 3 years, then started to see some PSA. .05.....06 ... Eventually climbed to .25 in Feb/2025, which triggered follow up treatment, starting in Late March 2025. Orgovyx for 6 weeks then 25 radiation treatments which ended 6/25/25. I am scheduled for ADT for 6 months,ending around Oct .1. My question is- is 6 months the norm?
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Expect lots of fatigue, prune type skin, weight gain, shrunken Peter. Been there done that. It’s not fun.
Let’s test your cockpit skills- what to when Cessna stalls and right wing falls with nose of aircraft pointing down.? This will inform me of your piloting skills- go for it my Canadian buddy. LOL
"what to when Cessna stalls and right wing falls with nose of aircraft pointing down"
Ailerons neutral. Correct with opposite rudder first, then yoke forward to break the stall. Increase power and gently recover to level flight.
Next question, instructor? 😉
(I could have included closing the throttle right after ailerons neutral, but that kind of stall usually happens on approach when you're already at low power, so there's no point making it more complicated than it needs to be.)
"Orgovyx and Lupron work almost exactly the same. I’ve been on both of them. There’s been no difference in any reaction/side effect."
True: the side-effects of low testosterone are similar, regardless of what's causing it.
The main difference is that Orgovyx is a GnRH receptor antagonist like Firmagon (they both block glands from receiving gonadotropin to stimulate testosterone production) while Lupron is a GnRH analogue or agonist (it mimics gonadotropin to desensitise the glands).
The downside of a GnRH agonist is that it causes an initial testosterone surge before the testosterone falls, and that is potentially a huge problem if your prostate cancer is already in a precarious situation (e.g. my metastasis was compressing my spinal cord); in that case, a GnRH antagonist like Firmagon or Orgovyx is a safer choice. There are some ways to block that surge with additional medications, but they still delay the actual testosterone *reduction*, so it's still longer before your cancer can start responding with Lupron than it is with Firmagon or Orgovyx.
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1 ReactionDang, I want a brain transplant with North.
I had been doing OK during my 4th year on Eligard, but then recent HDR Brachy + doubling the dosage of Flowmax + starting Xtandi is kicking my butt. Yesterday I took 4 naps. A few days ago I took my morning shower twice. I do still remember my wife's name, though.
I'll be chatting with my Mayo doctor in about a month, and if things aren't improving by then, I'll ask him about Nubeqa or other options.
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1 ReactionThank you for that information. We’ll discuss with my husband‘s oncologist next week. The main concern is the rise in the PSA. Dana Farber was not happy until he went down to 0.02. (If I’m printing that correctly). It is now at 0.01. They told him the chance of spreading at a higher number, was likely. He was diagnosed on Valentine’s Day, of this year, 2025, been on the medication’s as of 1 March.
Oh yeah, lots of naps the first 18 months or so for me too. I could think clearly, but I still got tired a lot until my body adjusted.
Thanks very much for that info. Good for you.!! I think I planted the seed after he had his blood transfusions, and took two months, to recuperate from it. And perhaps still is somewhat He wasn’t thinking straight at the time and I didn’t want him on the interstate, to go see his brother and sisters, 50 miles one way. He accused me of gaslighting him. My husband was a design engineer for NASA and an inventor and has patents and he does sudoku also, but occasionally uses the eraser. In my mind, I’m thinking, and because he’s never had a health issue in 84 years, he’s thinks he is doomed! I reminded him of my hot flashes, and told him to suck it up. He has cancer stuck in his brain, and he doesn’t want it. Since my original post, we ran into a guy at the coffee shop with his 40-year-old 10 speed bike. He had gone in for some Chinese food next-door and was smoking a cigarette. My husband was asking him about his bike because he had one just like it at one time. He’d ridden from Boston to East Haven, Connecticut one day, just for fun. This guy said he’s been in the Navy, for four years, had his chest opened, three times, had an abscess removed on his backside, and was in the hospital seven weeks, and had a colostomy bag which is now gone. He is 72. He looks 90. I said to my husband, “I’m thinking your situation doesn’t seem nearly as bad as this guy.
After all, that guy is driving with his brakes on😳”. My husband also never took a pill in his life. we both know it’s hard, really hard, but I don’t think it’s the end.
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1 ReactionForever. Advanced, Stage 4, 10+ PSA. Gleason 8, pain beyond belief. ER Dock thought I was a goner. 4.7 Year along, still getting ADT injections every six months. Oncologist told me "Forever."
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1 ReactionIn this case, he had already been on Orgovyx, So if he switched the lupron, it would not cause a problem.
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