← Return to Adding a second medicine question

Discussion
pjsatz avatar

Adding a second medicine question

Prostate Cancer | Last Active: Jul 19 9:28pm | Replies (37)

Comment receiving replies
Profile picture for pjsatz @pjsatz

I did not do well on Yonsa. I took a half dose of Yonsa and methylprednisone twice daily for a few days but started to get high blood pressure, headache and unsteady, effects were similar to abiraterone but probably not quite as bad.

Am also on Orgovyx. I may start on Nubeqa. I will be on medicines for 18-24 months, am 3 1/2 months on Orgovyx and am in radiation.

I am wondering what happens when I try to get off an ARSI like Nubeqa? Nubeqa is often prescribed indefinitely. Does anyone have experience getting off of the first or second generation ARSIs while still hormone sensitive? Hoping I will still be hormone sensitive at that point and can attempt to finish treatment as doctors are aiming for curative intent. Do the blocked androgen receptors come back ultra sensitive and increase my risk in the long run?

Nubeqa is actually not approved for what I have non metastatic hormone sensitive. I am oligometastaic with localized 2 lymph nodes positive and hormone sensitive. There are no test results yet for my scenario but the doctors are willing to prescribe Nubeqa for me as I am sort of in a grey area in terms of metastatic.

Thank you,

Phil

Jump to this post


Replies to "I did not do well on Yonsa. I took a half dose of Yonsa and methylprednisone..."

You can Just drop ARSI’s without any tapering. You do have to taper prednisone, however if you took abiraterone.

I’m a little puzzled, You say you have non metastatic hormone sensitive, But then, in the next sentence you say you are oligometastatic. That means you are metastatic hormone sensitive. You have up to five metastasis, That takes away the “non”