I've been reading posts about folks struggling with GI symptoms from the GLP-1RAs for months, as I did, and someone has finally done the necessary work to demonstrate that it really helps to ramp up based on our individual side effect profiles rather than the standardized path: https://diabetesjournals.org/care/article-abstract/doi/10.2337/dc25-0690/162990/Gradual-Titration-of-Semaglutide-Results-in-Better?redirectedFrom=fulltext