Ibuprofen is the worst medication to take for CKD. Nothing with Nsaids should be taken with kidney disease. When I was first diagnosed with kidney stones I was told to take 800mg of ibuprofen every 6 hrs. That is what helped my CKD escalate. That was in 1997. I am now Stage 4 Severe but am told that everything is fine as long as I stay away from salt, high potassium foods and ibuprofen. My eGFR2 value is stable at 29. BUN 44
Creatinine 1.80 Uric Acid 8.8. I had an excruciating gout attack waking me up from a deep sleep last week. It lasted 2 days. So it seems something is getting worse. But none of my doctors seem alarmed.
You also have to be careful with diuretics as this can cause potassium and uric acid to go wacky. But from what I have been told and researched, Jardiance and Farxiga are great for both T2 diabetes and kidney disease. I am on Farxiga and it will makes you pee like a racehorse. So make sure you drink plenty of water. I have to wear diapers 24/7 so it is somewhat of a pain but if it works it is definitely worth it.
I also have grandparents and great-grandparents who died of kidney disease.