Thanks, when I had colorectal surgery for cancer I went to the wrong surgeon. She left me with a colostomy and cut the nerve to the bladder which causes it to not empty so I have to self catheterize. No matter how much I wash with dial soap, use benzakonium wipes, a anti microbial perineal spray, wash my hands with dial soap, use a sterile catheter each time and try not to contaminate it (this is hard) I still get UTI’s frequently. I take cranberry pills with D-Mannose but not the dose you recommended. I saw urologist at Mayo yesterday and he started me on methenamine hipp. Has anyone else taken this? If a bigger dose of D-Mannose worked I would rather do that. Thanks, in advance, for any comment.