I was on the big 3 for 16 months and the tinnitus I had before starting got a lot worse. Had to quit the meds because I also got neuropathy. Still have MAC and now need hearing aids and the neuropathy isn't going away after 10 months. Doing airway clearance and watchful waiting at this point because I can't tolerate the new med therapy my ID doctor wanted to put me on. Has anyone else experienced med problems and found a new med regimen that doesn't cause bad side effects?