Are you sure that what you have is a yeast infection? I had symptoms that were like a yeast infection or UTI (which I tested negative for both), but it turned out to be interstitial cystitis, causing the same sort of irritation. I went to a urologist, and they recommended estradiol cream, which worked like a charm. Plus, it's very inexpensive. The secret was not to follow the instructions on the package because that was too much and it burned, but my doctor said to use a small dime size dollop every other day and low, and behold all my symptoms disappeared. Now I only use it as needed.