My experience is very similar to @nopnrose. I was diagnosed with PMR and GCA in late June 2024. I started with 60 mg prednisone, and about 6 weeks later I started taking weekly injections of Actemra. I have a Medicare Advantage plan that covers Actemra with prior approval.

I wouldn't say that taking Actemra requires constant blood tests. I have a rheumatology appointment every 3 months, and have a blood test before each one. The blood tests mainly monitor inflammation levels, but sometimes they check liver function and cholesterol levels. I haven't had any issues related to Actemra.

Actemra has allowed me to taper the prednisone to 2 mg per day. I'll drop down to 1 in 4 days. I hope to be through with prednisone in a month. Unlike @nopnrose, I would say I am at 100% now. I feel much better now than I have in several years. Getting below 3 mg per day of prednisone made a big difference in how I feel each day.