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Prolia vs. Evenity

Osteoporosis & Bone Health | Last Active: Sep 11 4:59pm | Replies (56)

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@mayblin, it does seem as if definitive conclusions are impossible to draw and more studies are needed. Or as you put it in an earlier post, there are no answers -- at least not yet -- as to the risk/safety of Evenity where cardiac events are concerned.

Re: hrt. My endo refused for me because I am slightly more than 10 years out from menopause and have a heart condition. Likewise my gyn would not prescribe. Are you within the 10-year bounds?

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Replies to "@mayblin, it does seem as if definitive conclusions are impossible to draw and more studies are..."

Exactly, you summed it up well! Ideally, your case is best managed via interdisciplinary collaboration, where specialists work together to evaluate the risks of each drug in the context of your specific medical conditions.

I started HRT at 61, 11 years post menopause. The decision is now described as "individualized assessment and shared decision-making process". I wonder if your endo's take on HRT was based on your Tscore and/or FRAX score. In my view, your endo is the one to determine whether HRT is the appropriate agent in managing your osteoporosis, while your cardiologist and obgyn are best suited to assess the potential risks for you.

HRT is generally used as an antiresorptive but is not officially indicated for treatment for severe osteoporosis. It can improve bmd to a certain extent, particularly during the first two years of therapy. So, if you are aiming for significant bmd gains in the near future, your original question still stands, a challenging one, indeed.