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Prolia vs. Evenity

Osteoporosis & Bone Health | Last Active: Sep 11 4:59pm | Replies (56)

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Thank you SO much for this info, @mayblin. How did you find this stuff? I have been digging around and digging around and came across nothing, nil, nada! You're a genius as far as I'm concerned.

I called both Amgen and Radius Health (Tymlos manufacturer) for recent info on cardiac events and post-Tymlos bmd loss, and neither the Amgen nor the Radius rep could offer me any information. In fact, the Amgen nurse told me there was no cardiac event info from one of the Amgen-sponsored Evenity studies in the prescribing information pamphlet. So wrong!

Many thanks, again...

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Replies to "Thank you SO much for this info, @mayblin. How did you find this stuff? I have..."

Haha, just happy I could help! The reason you couldn't find the information you're looking for is, because it doesn't exist!

I might eventually need evenity, but for now I'm keeping an eye on updated data regarding its cvd risk, as I have existing atherosclerosis. I came across a retrospective study based on post-marketing data that you might find useful:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11647516/
Table 1 provides a breakdown of existing medical conditions and medication histories. In the discussion section, the authors also shared their interpretations of the cvd findings from ARCH trial (linked video in my previous post), along with limitation of their retrospective analysis.