← Return to Estradiol for vaginal atrophy after breast cancer. Is it safe?

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Kensiejames: I am just looking at your March 2024 comment in July 2025. Your specifics are SO HELPFUL. And relieving. I am 3 years after estrogen receptor+ breast cancer/chemo/radiation and am on Letrozole. (And I'm in my late '70's.) I read about estrogen cream for the vaginal dryness that keeps me from intercourse with my husband, and queried my oncologist via my electronic chart. She didn't reply personally, her RN did. She said they thought it was safe and offered to phone in a prescription for me. That's it. There are some women's doctors who are good at their specialty but really don't know how it feels to have cancer, and don't appreciate how much we REALLY DON'T WANT TO HAVE IT AGAIN. So anything that has "estrogen" in the name that we're thinking of trying feels scary unless we have reassurance from a professional that it really is safe. So--thank goodness for this site, and a breast cancer site on Reddit for helping us all have more peace of mind. Thank you, Kensiejames.

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Replies to "Kensiejames: I am just looking at your March 2024 comment in July 2025. Your specifics are..."

Hey there! I am just now seeing your post to me. I have to get better at checking in with this site. My humble opinion, the blood test to check your estrogen levels is very telling. My number is well below my oncologist expectations.
Recently, my PCP spoke out against my using estrogen creams. I understand his concern. Estrogen cream does get absorbed into your body. When I first started using, GYN had me at 1 gram a week, and my blood work showed estrogen level was above the norm for my age group . Scary for a breast cancer survivor.
So it does get absorbed into the bloodstream . For me, 1/2 gram every two weeks was just enough to solve my problem and keep estrogen levels in the negative numbers.
I am 20 years out now, and God willing I will remain in remission. 🙏🏻

Call me chicken, but as my oncologist says, DO NOT use anything with estrogen in it, so I don't. I use Replens and it works really well for me. No estrogen in it.