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Folic Acid for peripheral neuropathy

Neuropathy | Last Active: Aug 24 8:19am | Replies (16)

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It's part of my neuropathy supplements that I've shared before. I think it may help but not sure if it helps much by itself. I don't have pain with my neuropathy but I take most all of the supplements shown to help neuropathy that are listed on the Foundation for Peripheral Neuropathy - https://www.foundationforpn.org/vitamins-and-supplements-for-nerve-health/. **** EDITED Aug 8, 2025 - FPN updated website with new information, fixed broken link.

Methylfolate 400 mcg - methylfolate is the active form of folic acid. The administration of l-methylfolate has been associated with increased levels of nitric oxide, thereby increasing blood flow to the peripheral nerve tissue. -- https://www.hmpgloballearningnetwork.com/site/podiatry/blogged/why-you-should-consider-use-supplements-management-diabetic-neuropathy.

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Replies to "It's part of my neuropathy supplements that I've shared before. I think it may help but..."

Hi John,
When you say "methylfolate is the active form of folic acid", what does that mean?

I take 100mg folate daily.

I also take b-1 and b-6. I used to also take b-12 but my tests kept coming back showing my b-12 levels were too high.

Thanks!