It probably is a good idea to leave the skin uncovered, but the Ostomy nurse said to change the pouch first thing in the morning before any food or drink so there is minimal to nothing coming out of the stoma. I use the adhesive remover first, then an ivory soap wash, then a clear water, then air dry. Then I proceed with the barrier procedure which was recommended by Coloplast. Procedure is easy for me as it is my husband who had the Iliostomy. He has never changed the pouch.