← Return to rotation of Bactrim & doxycycline. Gut is torn up. Help!

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Profile picture for Sue, Volunteer Mentor @sueinmn

Let's clarify please, when you say MAI do you mean Mycobacteria Avium Intracellulare? If so, the is part of the infective group known as MAC (Mycobacteria Avium Complex) or NTM (Nontubercular Mycobacteria.)
Are your culture still positive after 10 months on your drug regimen? If so, have the sputum samples been submitted for drug sensitivity testing to be sure you are using the correct antibiotics to actually clear the infection?
What sort of improvement are you seeing? Improved CT, less cough, clean culture, etc.

Please excuse my curiosity, but in seven years on Mayo Connect and NTM-ir, I have never seen this particular combination of meds used.

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Replies to "Let's clarify please, when you say MAI do you mean Mycobacteria Avium Intracellulare? If so, the..."

Goodness, I feel like I am doing all of this wrong. I have had improved Health; improvement has been seen on CT scan. I will see my pulmonologist in three weeks and I imagine sputum cultures will be taken. So, what is the gold standard treatment in your opinion?

Me neither. Bactrim and doxycycline are not on the usual lists of first line or second line antibiotics for MAI or MAC. They are sometimes prescribed for other NTMs like m. fortuitum. What matters most of course is if they are helping. Best of luck to all.