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Negative Turn in a Long Journey

Pancreatic Cancer | Last Active: Oct 1 5:03pm | Replies (102)

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He had targeted radiation Monday through Friday for 3 straight weeks. Caused so much fatigue that he was looking forward to getting back on chemo. Never had neuropathy yet. Having the Gemabraxane every 2 weeks vs 3 on, one off was a game changer as far as quality of life. They switched to every other because of low platelets. He gets a romaplastin shot every week now to enable the every two week chemo. He didn’t need the shots nearly as often prior to radiation.
He has KRAS G12V

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Replies to "He had targeted radiation Monday through Friday for 3 straight weeks. Caused so much fatigue that..."

Wonderful! Maybe that intense radiation helped. I had targeted radiation 3 sessions over a course of 6 days. My antigen was low normal for almost 6 months after that treatment. However, immediately after 6 months and 1 skipped gem chemo session a new lesion grew adjacent to the one that was ablated (radiated). My gut feeling is that maybe the margins for radiation were too narrow? I'll never know because I'm no longer with city of Hope, Irvine. I'm opting for histotripsy now. As far as your husband's treatment - I must say that's miraculous! My science background is always thinking black and white and what's logical, but sometimes I get thrown by stories by fellow members like your husband and @199 where I say there's something miraculous going on. I was on gem-abraxane (plus cisplatin for a few months) for nearly a year before neuropathy hit me very bad and I was switched to just gemcitabine. Wishing you both continued success!