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Severe itching on hands and feet during Taxol chemo Treatments

Breast Cancer | Last Active: Jul 13 1:06pm | Replies (14)
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Thank you so much. I am on Gabapentin 300mg and Claritin at bedtime and that takes me to the morning. Wake up and feel ok, but start itching about an hour later. So, Zyrtec and pepcid in the morning was added. Also I am appling Benadryl during the day. I am doing fairly well today after 5 awful days!!

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Replies to "Thank you so much. I am on Gabapentin 300mg and Claritin at bedtime and that takes..."
beebe | @beebe | Jul 9 1:01pm

I am passing this information on in case you have day time itch. Gabapentin reaches its peak effectiveness after you have taken it for 4 weeks. The effect of one dose will only last 6-8 hours, that is why I take 100mg three times a day.
The reported half-life (the time it takes for 50% of the drug to be metabolized) is 5 to 7 hours, which necessitates a dosing frequency of 3 to 4 times daily for it to be effective.
It is great that antihistamines during the day appear to be helping you, I was not so fortunate:)

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