My wife complained of memory loss long before I noticed it. And I think her decline has been slow and subtle, with changes noted more in retrospect than in real time. She has not been tried on any of the limited meds currently available. My professional experience was not gratifying and the side effects are troublesome to many. It has been discussed with her primary care physician, who feels much the same as I do. My wife has a masters degree and taught elememtary education 40 years. She spends her time doing crossword puzzles and sudoku. One other observation that is obvious is that she cannot follow the plot of TV dramas and movies, so she mainly watches new shows and talk shows. We watch Jeopardy together, and she occasionally blurts out a correct answer to a difficult question. This is a strange and highly complex and variable spectrum of "diseases". Your writing skills and background suggest you are highly educated, and I believe highly educated/intelligent people mask their disease for a long time. I wholly support your path to delay, defer and defeat your condition. So far evidence supports that physical activity, social engagement and mental exercises are helpful. I think the real hope is in a medical breakthrough in treatment and/or prevention. We just have to hang on long enough for that to happen. I wish you the best. I'm 81 and trying to stave off my own decline (nothing noticeable at this time mentally but plenty physically).