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Decide against aromatase inhibitors?

Breast Cancer | Last Active: Aug 27 10:53am | Replies (124)
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Profile picture for briarrose @briarrose

Well, this is good news to hear from the Mayo Clinic.
I am very concerned, about 2 major side effects from Anastrozole: Developing osteoporosis and since I have ischemic heart disease, my angina increasing or this AI will induce a heart attack or stroke.

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Replies to "Well, this is good news to hear from the Mayo Clinic. I am very concerned, about..."
jardinera25 | @jardinera25 | Jul 10 11:16am

I too am concerned about cardiac issues with the AI's; my risk is with hypertension, and when trying 2 different AI's (Letrozole & Anastrozole) I watched over several months as my numbers increased requiring more BP meds. Then it suddenly changed to my having Labile Hypertension, where it goes extremely high to very low. I'm 75. So have gotten off of them & am now on Fluvestrant injections, which is shrinking my chest wall tumor by 2/3 so far.
This article mentions CVD risks with AI's: https://pmc.ncbi.nlm.nih.gov/articles/PMC9181297/
Hard decisions, I know.
Hoping for the best for you! Patty

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