Hi, @hollygs: I took a break from thinking about osteoporosis drugs for a few days -- just couldn't handle it anymore -- so pardon my slow response. I am going to call Amgen tomorrow and see if I can get a few remaining questions answered. I had hoped my cardiologist would be willing to contact my old doc, the research director for Prolia & Evenity at Amgen, but I haven't heard back. I have an appointment with him (cardiologist) in a little over 2 weeks and will try to talk to him about this in person. I have unfortunately been trained (by long history with way too many doctors) not to ask a physician to go outside his normal scope or do anything "extra," so I am feeling a bit intimidated about asking cardiologist to extend himself and see if he can get something more than the usual warning about giving Evenity to heart patients.

I am scared about how long I can be off Tymlos before I start losing any gains. My endo & rheumy were kind of vague about it, so I might have to call the manufacturer.

I go for my Entyvio infusion (for UC) this week, and am grateful for your suggestion re: talking to the infusion center staff for a physician recommendation. And I never would have thought of Nextdoor, so thanks for that, too!

As to sequence, I really hadn't gotten that far. I was hoping to do Evenity, and if I reacted badly, I would succumb to Prolia. I'm really trying to avoid the bisphosphinates; my sister has jaw necrosis from Fosamax, and I don't know if that might be a family tendency. And since I have some necrosis in my hips, I am fearful of the dreaded femur break. Those were some of the other reasons I was wanting to avoid Prolia.

So, I still have some searching to do. I will keep you posted. Meantime, thanks again, and know I'm wishing you all the best of health! 🙂