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Exercise Oncology...what say you?

Prostate Cancer | Last Active: Aug 10 4:35pm | Replies (77)

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You bring up a great point that needs some explanation.

Many observational studies have found NO association with vigorous exercise and a reduced risk of being diagnosed with prostate cancer.

A comprehensive 2018 meta-analysis of 48 cohort and 24 case-control studies (151,748 prostate cancer cases) found no association between total physical activity and prostate cancer incidence.

However, a subgroup analysis, in that meta-analysis, showed that vigorous physical activity was associated with a 25% reduced risk of advanced prostate cancer.

A 2004 Harvard Health Professionals Follow-Up Study followed 47,620 men over 14 years. Men aged 65 or older who engaged in ≥3 hours per week of vigorous physical activity (e.g., activities such as running, cycling, or swimming) had a 67% lower risk of advanced prostate cancer, as compared to those with no vigorous activity.

However, no significant association was found between vigorous exercise and total prostate cancer incidence.

This suggests vigorous exercise may specifically reduce the risk of aggressive forms of prostate cancer but not its initial diagnosis.

The ERASE trial was particularly important, because it addressed men already diagnosed with localized PCa.

As odd as it sounds, the science indicates that men diagnosed with PCa are the beneficiaries of a ramped up vigorous exercise treatment program….. however, vigorous exercise does not prevent one from acquiring PCa.

…a very important difference to understand.

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Replies to "You bring up a great point that needs some explanation. Many observational studies have found NO..."

Excellent points and excellent distinctions - thank you.