Yes. I had my third shot last week and am awakened every night with pain in my knees, hips, and elbows and am very stiff on getting up. I have not been getting headaches, though.

I am hoping that it will dissipate as time goes on. I really need this treatment so I will continue even with this side effect. It can be challenging, though. I try to stay hydrated and active although I had to move my exercise workout from first thing in the morning to a bit later in the day due to the discomfort.

I am 64 and have been on osteoporosis meds for 7 years (Fosamax, Tymlos, Forteo). I will likely do Reclast after the Evenity. I am unwilling to go on Prolia at my age even though the doctor suggested it as her preferred option after Evenity. Perhaps when I am older.