My story is very similar
I had my prostate “ successfully”removed in 2011. Went six years undetectable PSA. Because of my general good health and my doctor retiring, I didn’t go to a doctor for 5 1/2 years. In October last year I was found to have a PSA of 37. By the time I got to MD Anderson in January it was 168. I have high volume metastatic prostate cancer with extensive metastasis to spine ribs both femur pelvis right arm and maximal bone in face (plus multiple lymph nodes).
I am now at Houston Methodist and on Orgovyx and Nubeqa.
My PSA was .07 as of last month. So yes, a rapid drop indeed can happen.
I’ve decided to not do chemo and pray that I can hold my PSA low long enough to keep the cancer idle until better treatments come around.