I had 10 cycles of chemotherapy, the norm is 4 to 6 cycles. I voluntarily asked for the additional cycles. Everyone's body is different and will react differently to chemo treatment. For me, I feel it has taken over two years to start feeling better. It is the ADT and ARSI's that cause the fatigue. You have to have a strong will to fight. There is a cancer personality. Some people are tough and fight through cancer with a will to beat it. Others are more docile and just struggle. I wanted more chemo cycles because I could handle it and I wanted to carpet bomb the cancer. Prostate cancer cells in the body are all different. You have adenocarcinoma, but each person adenocarcinoma cells are different. Some have aggressive cancer cells and no matter what the cancer fights back. Some cancer cells are tough up front but if you fight back hard enough it gives up. Some cells hang back and wait to mutate into something else allowing it to survive your treatment. That is why I choose 10 cycles. I wanted to kill as many cells as possible leaving nothing to chance. I killed a lot of healthy cells along the way but for me it was worth it to win this battle. I was diagnosed denovo high volume to the bone (spine, ribs, hips, shoulders femurs etc.). I lit up like a Christmas tree. I am now 3 years into my treatment and I am still undetectable and my latest bone scan showed that the metastases have shrunk and disappeared for the most part. I call it a miracle. I work every day sometime 12-13 hours a day. It is your choice but ask your doctor what are the standard number of chemo cycles and they will tells you 6 was chosen randomly. Studies have shown 10 or more chemo cycles results in greater overall survival. It is a matter of can you handle it. Remember, we are getting palliative treatment not curative. So, it is up to us to push the doctors to get the most treatment as possible for our overall survival.