PSA raising after RP

Posted by konana @konana, 6 days ago

I had RP (Radical Prostatectomy) surgery 11.5 years ago. For the first ten years, my PSA fluctuated between 0.03 and 0.09. One year ago, it rose to 0.14. In subsequent quarterly tests, it increased to 0.16, then to 0.25, and afterwards decreased to 0.2, and most recently dropped to 0.13. My next test is in 6 months. Has anyone had a similar experience?

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Lots of people have similar experiences to what you’re having. Usually, when the PSA hits .2 after A prostatectomy they want to do salvage radiation. In your case, you’re showing that your PSA is not pointing to a problem that has to be addressed right away.

I would be concerned with one thing, Sometimes prostate cancer doesn’t produce PSA, In around 10% of cases. It could be you are one of those cases and you’re just not producing much PSA. In those cases, getting a FDG scan can find cancer that can’t be found with a PSMA PET scan.

It could also be nothing, Though rising to 2.5 is pretty high after a prostatectomy.

Took 3 1/2 years after surgery before cancer came back and I had to have radiation.

Be aware that prostate cancer does go dormant for years and then comes back for some people.

Lifestyle can affect prostate cancer. I know people that have changed their diet completely, and it has reduced their cancer Or kept it from growing. In Australia, they have a broccoli soup that if you drink once a week can prevent your prostate cancer from growing and spreading.

REPLY
@jeffmarc

Lots of people have similar experiences to what you’re having. Usually, when the PSA hits .2 after A prostatectomy they want to do salvage radiation. In your case, you’re showing that your PSA is not pointing to a problem that has to be addressed right away.

I would be concerned with one thing, Sometimes prostate cancer doesn’t produce PSA, In around 10% of cases. It could be you are one of those cases and you’re just not producing much PSA. In those cases, getting a FDG scan can find cancer that can’t be found with a PSMA PET scan.

It could also be nothing, Though rising to 2.5 is pretty high after a prostatectomy.

Took 3 1/2 years after surgery before cancer came back and I had to have radiation.

Be aware that prostate cancer does go dormant for years and then comes back for some people.

Lifestyle can affect prostate cancer. I know people that have changed their diet completely, and it has reduced their cancer Or kept it from growing. In Australia, they have a broccoli soup that if you drink once a week can prevent your prostate cancer from growing and spreading.

Jump to this post

I really appreciate it; your explanation was very illuminating

REPLY
@jeffmarc

Lots of people have similar experiences to what you’re having. Usually, when the PSA hits .2 after A prostatectomy they want to do salvage radiation. In your case, you’re showing that your PSA is not pointing to a problem that has to be addressed right away.

I would be concerned with one thing, Sometimes prostate cancer doesn’t produce PSA, In around 10% of cases. It could be you are one of those cases and you’re just not producing much PSA. In those cases, getting a FDG scan can find cancer that can’t be found with a PSMA PET scan.

It could also be nothing, Though rising to 2.5 is pretty high after a prostatectomy.

Took 3 1/2 years after surgery before cancer came back and I had to have radiation.

Be aware that prostate cancer does go dormant for years and then comes back for some people.

Lifestyle can affect prostate cancer. I know people that have changed their diet completely, and it has reduced their cancer Or kept it from growing. In Australia, they have a broccoli soup that if you drink once a week can prevent your prostate cancer from growing and spreading.

Jump to this post

I really appreciate it; your explanation was very illuminating

5 Tem 2025 Cmt 19:12 tarihinde Mayo Clinic Connect <
nf+6bc49e7f+60523327@n1.hubapplication.com> şunu yazdı:

> ## reply above this line ##
>
>
> Mayo Clinic Connect
> *Comment* posted by @jeffmarc
> < https://connect.mayoclinic.org/member/00-6018ad2132cc535a416722/?utm_source=connect.mayoclinic.org&utm_medium=email&utm_campaign=new_comment&utm_content=new_comment_intro_userlink&gt;
> on discussion "PSA raising after RP".
>
> Lots of people have similar experiences to what you’re having. Usually,
> when the PSA hits .2 after A prostatectomy they want to do salvage
> radiation. In your case, you’re showing that your PSA is not pointing to a
> problem that has to be addressed right away.
>
> I would be concerned with one thing, Sometimes prostate cancer doesn’t
> produce PSA, In around 10% of cases. It could be you are one of those cases
> and you’re just not producing much PSA. In those cases, getting a FDG scan
> can find cancer that can’t be found with a PSMA PET scan.
>
> It could also be nothing, Though rising to 2.5 is pretty high after a
> prostatectomy.
>
> Took 3 1/2 years after surgery before cancer came back and I had to have
> radiation.
>
> Be aware that prostate cancer does go dormant for years and then comes
> back for some people.
>
> Lifestyle can affect prostate cancer. I know people that have changed
> their diet completely, and it has reduced their cancer Or kept it from
> growing. In Australia, they have a broccoli soup that if you drink once a
> week can prevent your prostate cancer from growing and spreading.
> VIEW & REPLY
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REPLY
@jeffmarc

Lots of people have similar experiences to what you’re having. Usually, when the PSA hits .2 after A prostatectomy they want to do salvage radiation. In your case, you’re showing that your PSA is not pointing to a problem that has to be addressed right away.

I would be concerned with one thing, Sometimes prostate cancer doesn’t produce PSA, In around 10% of cases. It could be you are one of those cases and you’re just not producing much PSA. In those cases, getting a FDG scan can find cancer that can’t be found with a PSMA PET scan.

It could also be nothing, Though rising to 2.5 is pretty high after a prostatectomy.

Took 3 1/2 years after surgery before cancer came back and I had to have radiation.

Be aware that prostate cancer does go dormant for years and then comes back for some people.

Lifestyle can affect prostate cancer. I know people that have changed their diet completely, and it has reduced their cancer Or kept it from growing. In Australia, they have a broccoli soup that if you drink once a week can prevent your prostate cancer from growing and spreading.

Jump to this post

REPLY
@jeffmarc

They grow some super broccoli in Australia. . It’s only available in Australia as far as I know.

Here is info on how it affects genetic changes

Jump to this post

REPLY
@jeffmarc

They grow some super broccoli in Australia. . It’s only available in Australia as far as I know.

Here is info on how it affects genetic changes

Jump to this post

Thanks Jeff - as always you have great information that nobody is talking about *sigh ! WHY is nobody making powdered supplement of THAT kind of broccoli is beyond me !

I bought broccoli supplement for my husband as soon as I read about it in a cancer prevention book, but it is made of regular broccoli. I guess better to take any than none.

REPLY

Konna- Like the Coffee? ...man ! I like that Kona Gold coffee from Hawaii ! With your PSA bouncing around . How old are you ? Any other health problems? What was your PSA before surgery ... and Gleason AFTER operation ? Its kind of strange that after 10 years you get a little bounce like this... but certainly not unheard of . I would maybe get a PSA every 3 months instead of 6 , just to get more data points while its bouncing about. Jeff makes a good point in the in some cases PC source stops or does not produce much PSA at all - these are usually super aggressive too . Something to be aware of , but not likely and its rare statistically. For some reason you have some activation of healthy or infected cells( they can be either or ) , sometimes healthy cells will push out a small amount of PSA ( Dr's feel this is my Case where I always have 0.030-0.042 in the back ground) . I have had radiation , 22 sessions and no ADT 3 years after prostatectomy .... as my PSA snuck up every so slowly to 0.14 . Then I hammered it with 22 sessions of External Beam Radiation . I am 62 now , 5 years ago I had operation. Did you ever get EBRT to pelvic. region? How many sessions ? Any other PC procedures you have had ? Let us know Sir ...God Bless !

REPLY
@surftohealth88

Thanks Jeff - as always you have great information that nobody is talking about *sigh ! WHY is nobody making powdered supplement of THAT kind of broccoli is beyond me !

I bought broccoli supplement for my husband as soon as I read about it in a cancer prevention book, but it is made of regular broccoli. I guess better to take any than none.

Jump to this post

I took both DIM and sulfurophane extracts from broccoli - “pharmaceutical grade” - for 2 yrs before my diagnosis. Didn’t do much cause here I am….or maybe I wouldn’t even be here at all?
If only they made a version with heavy cream and cheddar - then the extract could counter the effects of the ‘bad dairy’, right?😉🤞

REPLY
@heavyphil

I took both DIM and sulfurophane extracts from broccoli - “pharmaceutical grade” - for 2 yrs before my diagnosis. Didn’t do much cause here I am….or maybe I wouldn’t even be here at all?
If only they made a version with heavy cream and cheddar - then the extract could counter the effects of the ‘bad dairy’, right?😉🤞

Jump to this post

Ha ha, that is what my daughter says when I grumble about the fact that of alllll people it had to be my husband who got PC and needed a stent at 50 when he was eating Mediterranean diet his whole life, playing sports of all kinds and competitively, was always normal weight, taking supplements, did not even had high cholesterol or high BP, and even his cardiac scan score was zero when he had weird event with heart, does not drink or smoke or (you name it) . My daughter than always says "well, we do not know how bad it would have been if he was not having this lifestyle !!!" Maybe she is right, but it is really not fair. Well, as Irish people wisely say: "There is no justice on this side of a grave", and I know what will be my first question at the "Pearly Gates"entrance - WHAT THE *ELL ARE YOU GUYS DOING UP HERE ??? XP lol lol

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