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Treatment for Prostate Cancer Metastasized to Bones

Prostate Cancer | Last Active: Sep 24 7:12pm | Replies (171)

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new here Oct 2nd was diagnosted with stage 4 metastasized prostate cancer spread to bones. m on eleguard and nubequa. did 6 months of chemo. question doing lots of on line research, trying to be my own advocate asking questions telling doctor to inform for next steps. im getting ready for genetic testing. also. i guess im trying to be informed what anyone else has gone through with stage4 metastasized prostate bone cancer so when i do go to my doctor i have a better understanding of what to ask. what were some of your steps i:e just drug therapy, targeted radiation, ect. any help appreciated. im 55 and want many more years, dont want to lose out by being uninformed,

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Replies to "new here Oct 2nd was diagnosted with stage 4 metastasized prostate cancer spread to bones. m..."

I'm sorry for your news.

The big question is how many metastases they discovered. If there are just a few, then you're oligometastatic, and they may choose to treat the individual metastases with radiation; if they're widespread, they may choose chemo up front to knock it back a bit. It's also increasingly common to give a "curative" dose of radiation to the prostate, even at stage 4, because studies have shown a significant survival benefit (that's a big change in thinking from 10 years ago).

They'll likely also put you on hormone therapy, including an ADT like Orgovyx and an ARSI like one of the -lutamides or Abiraterone. If your PSA responds to that, then the cancer is still "castrate-sensitive"; if/when it stops responding, your cancer has become "castrate-resistant", and they may suggest other treatments like additional chemo or Pluvicto.

Don't be discouraged. I was 56 when I was diagnosed with de-novo stage 4 prostate cancer metastasised to my spine, and I was certain my life was drawing to a close. I'm 60 now, with no evidence of disease (that doesn't mean I'm "cured", but modern treatments can put many of us in deep functional remission almost indefinitely).