In January of 2024 I received my one and only reclast infusion. I had the extreme reaction some others have had about 10 hours after-the rib, back pain, "hit by a truck" feeling which lasted about a day then slowly abated. However, about 2 months later I began with musculoskeletal pain which only affected my right leg-hip to ankle. It began a cycle of flareups that would last a month or more then go away almost completely only to return a couple of months later. The pain eventually settled in my right knee which has had some extreme flareups. Xray showed osteoarthritis, bone on bone laterally. I received a steroid injection and PT which helped but it still flares up depending on my activity, especially at night. Like you, I was very active before and this has had a huge impact on my life. I will note that I had a similar reaction as far as pain goes when I took Fosamax years ago and I stopped that weekly pill after 4 months with no recurrence until the Reclast. I took a chance, knowing this, and regret that decision. For now, I do the exercises PT assigned to strengthen my muscles that support the knee with hopes of avoiding a knee replacement. I am holding off on another steroid injection as you can only have so many and concern how it may affect my osteoporosis. I wish you the best and some answers so hope to hear how you do.