Replies to First – a big hug. My husband was diagnosed two years ago Gleason 4 + 5….

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Prostate Cancer | Last Active: Jul 4 2:49pm | Replies (37)

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@ellen45

First - a big hug. My husband was diagnosed two years ago Gleason 4 + 5. He underwent radiation followed by what will be 2 years of Abiraterone + Prednisone and Lupron Depot. He has done fine - usual side effects but not horrible. Hot and cold flashes. He is 81. We are worried about what will happen after we stop the hormone therapy, but regarding your questions - it isn’t too bad to go through all of it. My husband doesn’t drive any longer because of glaucoma, we were in this together and are a team - you two will be a good team!

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Replies to "First - a big hug. My husband was diagnosed two years ago Gleason 4 + 5...."

jeff Marchi | @jeffmarc | Jul 4 12:18pm

I’ve heard from people that have been giving advice about prostate cancer for 15 years that if you switch from abiraterone to a lutamide after abiraterone fails (Your PSA starts rising) There’s only a 5% chance it works.

I took abiraterone For 2 1/2 years. It was pretty hard on my heart, And the side effects were definitely worse. During that 2 1/2 years my PSA was only undetectable one month. I went on Darolutamide And my PSA has been undetectable for 19 months, starting three months after I began Darolutamide. It also has a lot fewer side effects than abiraterone.

I mentioned all this because at 81 your husband needs to have the least side effects he can handle. Switching now may benefit him more than switching after Abiraterone fails.

Ask your doctor about it.

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